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Read full article about: OpenAI: "No, we haven't made GPT-4 dumber"

Is GPT-4 getting worse? Peter Welinder, VP Product at OpenAI, comments on the rumors: "No, we haven't made GPT-4 dumber. Quite the opposite: we make each new version smarter than the previous one," says Welinder. His hypothesis: "When you use it more heavily, you start noticing issues you didn't see before."

Still, he asked on Twitter for examples of where users felt GPT-4's performance had regressed. OpenAI will look into this, Welinder promises. One example from the comments, where GPT-4 only gives the correct answer after a second attempt, he claims is a bug.

Field reports of GPT-4 performance degradation have been around for a few weeks now, often pointing to a performance difference between access via API and via ChatGPT, where the OpenAI language model integration is regularly adjusted. The opacity of this process may also contribute to uncertainty among users.

Read full article about: RFdiffusion aims to revolutionize custom protein design

AI tool RFdiffusion, a neural network developed by the University of Washington, can rapidly design custom proteins with potential applications in vaccines, therapeutics, and biomaterials. The tool borrows principles from neural networks that generate realistic images, such as Stable Diffusion, DALL-E, or Midjourney, creating complex and diverse protein shapes when it "denoises" a random assortment of amino acids.

Although the designs show promise in early experimental tests, researchers are still working to improve the AI's ability to design proteins with more complex active sites and specific reactions. RFdiffusion is available on GitHub.