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Read full article about: Google's AI drug discovery spinoff Isomorphic Labs claims major leap beyond AlphaFold 3

Isomorphic Labs, Google DeepMind's AI medicine startup, has unveiled a new system called "Isomorphic Labs Drug Design Engine" (IsoDDE) that it says outperforms AlphaFold 3. According to the company, IsoDDE doubles AlphaFold 3's accuracy when predicting protein-ligand structures that differ significantly from the training data (see left graph below).

IsoDDE outperforms previous methods in structure prediction, binding pocket recognition, and binding strength prediction, according to Isomorphic Labs. | Image: Isomorphic Labs

Beyond structure prediction, IsoDDE can identify previously unknown docking sites on proteins in seconds based solely on their blueprint, with accuracy that Isomorphic Labs says approaches that of lab experiments. Isomorphic Labs also claims the system can estimate how strongly a drug binds to its target at a fraction of the time and cost of traditional methods. These capabilities could uncover new starting points for active compounds and speed up computational screening.

Isomorphic Labs says it already uses IsoDDE daily in its own research programs to develop new drug candidates. Details are available in the company's technical report.

Read full article about: Second xAI co-founder Tony Wu departs as Musk folds money-losing AI venture into SpaceX

After Igor Babushkin, another xAI co-founder has announced his departure. Tony Wu, who was responsible for developing the company's foundational models and reasoning capabilities, reported directly to Musk. He joined xAI from Google when the company was founded in 2023.

Wu is leaving after xAI recently allowed the creation of deepfake nude photos for weeks, only backing down under pressure from authorities. His departure likely has nothing to do with the controversies, though—the AI developer thanks Elon Musk for his support in his farewell post, referencing "all those battles we have fought together." Babushkin left xAI back in August 2025 and started his own AI safety fund. His departure followed several controversies around the xAI chatbot Grok, which drew attention for far-right statements, among other things.

The timing is still notable. SpaceX recently announced a takeover of xAI that values SpaceX at one trillion dollars and xAI at 250 billion dollars. The likely reason: xAI generates almost no revenue on its own, even though developing and running its models costs billions. Without major progress, xAI appears to have no clear path forward (but a ton of compute).

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Read full article about: OpenAI's first AI device won't arrive until 2027 as company ditches "io" branding

OpenAI won't be using the name "io" for its planned AI hardware devices. That's according to a court filing submitted as part of a trademark lawsuit brought by audio startup iyO, Wired reports. OpenAI had already scrubbed references to the project back in June 2025.

OpenAI VP Peter Welinder said the company reviewed its naming strategy and decided against "io." OpenAI also revealed that its first hardware device won't ship until the end of February 2027 at the earliest - later than previously indicated. No packaging or marketing materials exist yet.

OpenAI acquired the hardware startup from former Apple designer Jony Ive for $6.5 billion in May 2025. Over the weekend, a fake Super Bowl ad allegedly showing OpenAI's device made the rounds online. OpenAI spokesperson Lindsay McCallum told Wired the company had nothing to do with it.

Read full article about: Pony AI and Toyota begin rolling out 1,000 self-driving electric SUVs for robotaxi duty

Chinese robotaxi operator Pony AI and Toyota have kicked off commercial production of a self-driving electric car. The first of 1,000 fully electric, autonomous Toyota bZ4X compact SUVs has rolled off the assembly line at a joint venture plant run by Toyota and the Guangzhou Automobile Group. The vehicles are meant to help Pony AI hit its goal of expanding its robotaxi fleet to more than 3,000 cars by the end of the year. The bZ4X is one of three models Pony AI is deploying with its latest autonomous driving software across major Chinese cities.

The vehicles run on Pony AI's autonomous driving system, rated at SAE Level 4. That means the car drives itself completely within designated areas - no human needs to sit behind the wheel, hold the steering wheel, or watch the road. There are still limitations, though, such as restrictions on operating zones or weather conditions.

Even though the technology enables driverless operation, human support is still part of the equation. Right now, one person oversees roughly 30 vehicles and can step in if something goes wrong.

Pony AI competes with other Chinese robotaxi companies like Baidu and WeRide.

Read full article about: Anthropic's head of Safeguards Research warns of declining company values on departure

Anthropic is starting to feel the OpenAI effect. Growing commercialization and the need to raise billions of dollars is forcing the company into compromises, from accepting money from authoritarian regimes and working with the US Department of Defense and Palantir to praising Donald Trump. Now Mrinank Sharma, head of the Safeguards Research Team—the group responsible for keeping AI models safe—is leaving. In his farewell post, he suggests Anthropic has drifted away from its founding principles.

Throughout my time here, I've repeatedly seen how hard it is to truly let our values govern our actions. I've seen this within myself, within the organization, where we constantly face pressures to set aside what matters most, and throughout broader society too.

Mrinank Sharma

The Oxford-educated researcher says the time has come to move on. His departure echoes a pattern already familiar at OpenAI, which saw its own wave of safety researchers leave over concerns that the company was prioritizing revenue growth over responsible deployment. Anthropic was originally founded by former OpenAI employees who wanted to put AI safety first, making Sharma's exit all the more telling.

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The new Gemini-based Google Translate can be hacked with simple words

A simple prompt injection trick can turn Google Translate into a chatbot that answers questions and even generates dangerous content, a direct consequence of Google switching the service to Gemini models in late 2025.

Read full article about: ChatGPT now shows ads to free and Go users, with opt-out cutting daily message limits

OpenAI is rolling out ads in ChatGPT for users in the United States. The test targets logged-in adult users on the free and "Go" tiers. Plus, Pro, Business, Enterprise, and Education plans remain ad-free. Free-tier users can opt out of advertising, but doing so reduces their daily message allowance.

OpenAI says the decision comes down to high infrastructure costs. The company stresses that ads don't influence ChatGPT's responses, and conversations stay private. Which ad a user sees depends on the conversation topic, previous chats, and interactions.

Users under 18 won't see any ads, and ads won't appear around sensitive topics like health or politics. Users can hide individual ads, delete their ad data, and adjust personalization settings. Advertisers get aggregated performance statistics but have no access to chat logs or personal data, OpenAI says.

What will always remain true: ChatGPT’s answers remain independent and unbiased, conversations stay private, and people keep meaningful control over their experience.

Putting ads in chatbots is controversial, since the potential for manipulation is greater than with traditional search engines. OpenAI says it will keep ads clearly separated from content. Long term, the company plans to roll out additional ad formats.

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Read full article about: OpenAI says ChatGPT is growing again, plans new model this week

OpenAI CEO Sam Altman told employees in an internal Slack message that ChatGPT is once again growing by more than ten percent per month, CNBC reports. The last official number was 800 million weekly users in January 2026.

Altman also said an updated chat model for ChatGPT is set to ship this week. It could be the chat variant of GPT 5.3, which OpenAI released last week as the coding-focused version Codex. The model scores particularly well on agent coding benchmarks and is 25 percent faster, according to OpenAI.

The Codex coding product has grown roughly 50 percent in just one week, according to Altman (60% "Codex user", now confirmed via X), who called the growth "insane." It competes directly with Anthropic's popular Claude Code. OpenAI's new Codex desktop app in particular is likely to expand gradually beyond coding use cases, following a similar path to Anthropic's Cowork.

Comment Source: CNBC